Gluconolactone (PHA)
The gentle PHA — helps smooth and refine skin with less sting than AHAs.
INCI name: Gluconolactone
Best for skin
What it is
Gluconolactone is a polyhydroxy acid (PHA) — a larger, slower-acting cousin of AHAs. Because the molecule is bigger, it works more gradually and tends to sting less, which makes it a favorite for sensitive skin that finds glycolic or salicylic acid too harsh. It also has humectant and antioxidant qualities.
What it helps with
- Helps gently smooth and refine the look of skin
- Larger molecule — usually lower sting than AHAs
- Has humectant (water-attracting) qualities on top of exfoliating
- A softer entry point into acids for sensitive skin
Good for
- Sensitive skin new to acids
- Reactive skin that stings with AHA/BHA
- Dull, uneven texture
- A gentle routine
Pairs well with
Watch out
Gentler does not mean "no rules" — it can still increase sun sensitivity, so daily SPF applies. Start a few times a week and build up. If you already use a strong AHA/BHA, you usually do not need to stack a PHA on top the same night.
FAQ
Is PHA better than AHA or BHA?
Not better — gentler. PHAs like gluconolactone work more slowly and sting less, which suits sensitive skin. If your skin tolerates AHA/BHA and you want faster results, those still have their place.
Can sensitive skin use gluconolactone?
It is often the exfoliant of choice for sensitive skin because of the lower irritation. Still patch-test, start slow, and stop if it stings consistently.
Sources
The honest note: ingredients help — they don't treat medical conditions. For persistent skin issues, a board-certified dermatologist beats any product swap.